The calcitonin gene-related peptide family: form, function and future perspectives (2009)

Description: This book contains a comprehensive series of reviews on the calcitonin gene-related peptide (CGRP) family of peptides. This family of peptide hormones has a diverse and constantly expanding range of important physiologic functions, including regulation of blood calcium, vascular tension, feeding behavior and pain recognition.

This volume includes chapters on:

The adrenomedullin peptides and signalling

Ligand binding and activation of the CGRP receptor

Understanding amylin receptors

The CGRP-receptor component protein

The calcitonin peptide family

Genetic regulation of CGRP

Vascular actions of CGRP and adrenomedullin

Intermedin/adrenomedullin 2 function

CGRP and adrenomedullin as pain-related peptides

Amylinergic control of ingestive behaviour

Calcitonin receptors

This book discusses their receptors, physiological and pathophysiological functions and potential as clinical targets. It will appeal to researchers who study any of these peptides and those with an interest in migraine therapy due to the involvement of CGRP in this disorder. The book is unique because it brings together research on the whole peptide family for the first time in several years. It will be a useful reference volume for researchers in this area. This book will also appeal to researchers in the broader field of bioactive peptides.


Download
or
Mirror