Chemotherapeutic treatment of neoplastic diseases is often restricted by adverse systemic toxicity, which limits the dose of drug that can be administered, or by the appearance of drug resistance. Lack of selectivity is only one (albeit a major) obstacle hindering the optimisation of drug effectiveness. Others include inaccessibility of target, premature drug metabolism and allergic reactions. There is a great demand for innovative drug delivery systems that can better target antitumour drugs and that can overcome resistance in its many forms.

X-ray crystallography has long been a vital method for studying the structure of proteins and other macromolecules. As the importance of proteins continues to grow, in fields from biochemistry and biophysics to pharmaceutical development and biotechnology, many researchers have found that a knowledge of X-ray diffraction is an indispensable tool. In this new edition of his essential work, Dr. Jan Drenth, recognized internationally for his numerous contributions to crystallographic research, has provided an up-to-date and technically rigorous introduction to the subject.

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Medical Myths, Lies, and Half-Truths: What We Think We Know May Be Hurting Us. Dr. Novella's 24 revealing lectures are an empowering learning experience that will give you evidence-based guidelines for good health, will enhance your ability to be better informed about common medical myths, and will strengthen your skills at assessing the scientific truth behind medical information and advice—whether you're having an important conversation with your doctor or taking a trip down the medicine aisle of your local pharmacy.

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With its up to 500 trillion synaptic connections, your brain is easily the most powerful machine in the world. These connections are what create your thoughts, what drive your emotions, and what control your behaviors. Even more incredibly: This amazing machine is constantly changing through a process known as brain plasticity. And you can take advantage of this process to improve and enhance your brain's jaw-dropping powers—at any age. Brain plasticity, the secret to optimizing your brain's fitness, is one of the most revolutionary discoveries in modern neuroscience. While it was traditionally thought that our brains were fully formed by adulthood, the truth is that our life experiences continually shape and mold our brains in fascinating ways.

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This is a series of 468 videos that depicts and trains you in the various positions of a veterinary clinic (besides the veterinarian).

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